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Compounds

Cat No. Product Name Synonyms Targets
T8917 PAR-2-IN-1 IUN76750 Protease-activated Receptor
PAR-2-IN-1 (IUN76750) is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects.
T36286 Protease-Activated Receptor-3 (PAR-3) (1-6), human
TFRGAP-amide, human PAR-3-derived tethered ligand sequence which does not activate PAR-3 but rather activates PAR-1 and PAR-2, either in Jurkat or in other PAR-expressing cells.
T36293 PAR 4 (1-6)
PAR 4 (1-6) can be used for relevant research in the life sciences. Its product number is T36293 and CAS number is 225779-44-2.
T80240 Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biologically active peptide functioning as a selective agonist for Protease Activated Receptor 1 (PAR-1), a subtype of G-protein coupled receptors involved in mediating thrombin...
T36717 RWJ-56110 dihydrochloride
RWJ-56110 dihydrochloride is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4. RWJ-56110 dihydrochloride inhibits...
T74266 Protease-Activated Receptor-1 antagonist 2
Protease-Activated Receptor-1 Antagonist 2 is an orally active antagonist of protease-activated receptor-1 (PAR-1), demonstrating significant potency with an IC 50 of 7 nM. It exhibits favorable pharmacokinetic character...
T35955 PAR2 (1-6) amide (human) (trifluoroacetate salt) PAR2 (1-6) amide (human) (trifluoroacetate salt)
PAR2 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR2 and residues 37-42 of the full-lengt...
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